Undergraduate research, encompassing university education and research, is widely recognized for enhancing academic skills and career prospects. But does this competence translate to business practice? This study examines the influence of Course-Based Undergraduate Research Experience (CURE)–on career aspirations and entrepreneurship. Focusing on Japan—where over 90% of universities offer CURE— it analyzes questionnaire data from 733 participants in high schools, universities, and workplaces. Using Structural Equation Modeling (SEM) analysis, we explored the links between autonomy in high school, university CURE participation, career aspirations, and workplace entrepreneurship. Results reveal that individuals with greater autonomy are more engaged in CURE, which boosts career aspirations and entrepreneurial activities post-graduation. This study highlights the role of undergraduate research in shaping business careers and contributes to bridging entrepreneurship and education research. It underscores that university research benefits both academic and professional trajectories.
