This study examines the disparities between employees with and without disability, focusing on four forms of workplace mistreatment (verbal abuse, sexual harassment, threats, and humiliation) and multiple job and wellbeing outcomes. Using a large random representative sample of Canadian employees (N = 19, 609), we show that disabled employees are significantly more likely to experience all forms of mistreatment compared to their non-disabled counterparts. These employees also report higher stress levels, poorer health outcomes, lower job satisfaction and engagement, and higher job disengagement. These results highlight the need for inclusive policies that address workplace inequities and promote more equitable environments for vulnerable employees.